French national reference center for genetic deafness
Deafness is the most frequent form of sensorial defect; it is reported to impair 1 children over 1000 at birth; 1 over 700 before adult age and an important percentage of the adult population. Although deafness is not rare, it gathers an important set of genetic rare diseases. It is estimated that 80% of infant hearing loss have genetic origins. Concerning hearing loss in adult population, the genetic part is yet to be determined but will for sure be important. To date, more than 100 genetic forms of isolated hearing loss are clearly identified and more than 500 syndromes (including deafness) have been described.
Within the framework of the rare disease plan projects, the reference center for genetic deafness is attached to the SENSGENE rare diseases healthcare network (coordinated by Professor Hélène Dollfus, Strasbourg University hospital) and therefore carries out all the missions of the network in relation to genetic deafness. The reference center is also affiliated with the Rare craniofacial anomalies and ENT disorders European Reference Network (ERN).
> Learn more about the paediatric audiology research centre
On Tuesday, November 19 and Wednesday, November 20, 2024, the ACFOS association is organizing its 20th annual symposium on the theme: 10 years of neonatal hearing screening and early diagnosis: What has been achieved? What are the prospects?
> More information on the ACFOS symposium and online registration
Medical
team
Dr Sandrine Marlin
MD, PhD
Contact
us
Phone + 33 (0) 1 44 49 57 44
> Send a mail
When making an appointment, please mention Dr. Marlin’s name and specify if it is :
– a first appointment
– or a follow-up appointment
Patient
pathway
The reference center for genetic deafness (RCGD) is unique in France. It has been created in 2000 by Dr Sandrine Marlin and accredited during the first french rare diseases national plan in 2004.
Located in Necker Hospital (dedicated to children), the center coordinates a national network composed by 2 constitutive sites : in La Pitié-Salpétrière (dedicated to adult) directed by Dr Isabelle Mosnier and in Lille directed by Dr Catherine Vincent Delorme (children and adult) ; and 20 competence centers displayed in France (metropolitan and overseas). The network regroups clinical geneticists, ENT, and molecular biologists.
Each year the RCGD of Necker’s hospital receives 700 different families. The patient care is assured by a team composed with a geneticist doctor, a genetic counselor, a clinical psychologist, a nurse and a secretary, working together with the ENT departments of Necker and La Pitié-Salpêtrière, leaders in deaf patient care in France. The center is located in medical genetic Department of Imagine institute in Necker Hospital.
The RCGD and its national network have defined a patient care permitting the diagnosis for deaf children, teenagers and young adults improving the transition from children to adult hospital.
- Isolated genetic deafness of recessive transmission
- Isolated genetic deafness of dominant transmission
- Isolated genetic deafness linked to the X chromosome
- Mitochondrial genetic isolated deafness
- Isolated auditory neuropathies
- Syndromic auditory neuropathies
- Waardenburg syndrome
- Usher syndrome
- Pendred syndrome
- Branchio-oto-renal syndrome
- Stickler syndrome
- Noonan syndrome
- H syndrome
- 22q11 deletion syndrome
- CHARGE syndrome
- Franceschetti – Treacher Collins syndrome
- Goldenhar syndrome
- Monosomy 18q
- Wolfram syndrome
- Perrault syndrome
- Rosai Dorfman syndrome
- LADD syndrome
- KBG syndrome
- Branchio-oculu-facial syndrome
- Hypoparathyroidism deafness renal dysplasia syndrome
Physicians
Head of the reference center
Dr Sandrine Marlin
MD, PhD
Dr Natalie Loundon
MD, PhD
Dr Margaux Serey-Gaut
MD
Biologist
Dr Laurence Jonard
PharmD, PhD
Genetic counsellor
Souad Gherbi
Researcher
Sylvain Ernest
Psychologists
Jeanne Cador
Nurse
Fabienne Saint Jalmes
Secretary
Eva Leite Freire
Sensgene project manager
Afida Djabri
The National Diagnostic and Care Protocols (NDCP or PNDS in French) are best practice guidelines for rare diseases. The objective of a PNDS is to explain to the professionals concerned the optimal diagnostic and therapeutic management and the care pathway for a patient suffering from a given rare disease.
As provided for in the 2011-2014 second national plan for rare diseases, they are developed by reference and competence centers for rare diseases using a method proposed by the Haute Autorité de Santé (HAS).
The PNDS include a « summary for the treating physician » section.
- 22q11 deletion (2016)
- Rasopathies (Noonan Syndrome and related) (2016)
- Pendred syndrome (2021)
- Heimler syndrome (2021)
- Ear aplasia (ongoing)
- Trisomy 21 (in progress)
« Light4deaf: Natural history study of Usher syndrome in a cohort of patients followed longitudinally for 5 years »
Genetic study of isolated malformations of the cochlear nerves
Psychosocial determinants of the impact of deafblind disability on autonomy within the life course
« Secondary deafblindness: a multidisciplinary approach » university diploma
Rennes I university
University degree in otology and audiophonology of children
Paris Descartes university
Inter-university diploma in pediatric neurology
Paris-Descartes university
Inter-university diploma in dysmorphology, developmental anomalies and genetic polymalformative syndromes: diagnosis and care
Paris Diderot university
Master of Integrative Biology and Physiology
Pierre et Marie Curie university
Professional License LPC Coder
Pierre et Marie Curie university
EPU hearing aid
National College of Hearing Aids
Conference of 1.18.18: Genetic deafness in adults
Continuing medical education – Pitié-Salpêtrière
2021
– The simplified French Matrix. A tool for evaluation of speech intelligibility in noise.
I Prang, M Parodi, C Coudert, S Legoff, M Exter, M Buschermöhle, F Denoyelle, N Loundon
Eur Ann Otorhinolaryngol Head Neck Dis, 2021 Sep, PMID: 33422468 DOI: 10.1016/j.anorl.2020.12.003
– Auditory processing disorder in children: the value of a multidisciplinary assessment.
Isabelle Rouillon, Aude de Lamaze, Marlène Ribot, Gregory Collet, Théodora de Bollardière, Razane Elmir, Marine Parodi, Sophie Achard, Françoise Denoyelle, Natalie Loundon
Eur Arch Otorhinolaryngol, 2021 Dec, PMID: 33462745 DOI: 10.1007/s00405-020-06601-8
– Outcome for bilateral cochlear implantation in patients with congenital Cytomegalovirus infection.
C Courtois, M Blanchard, I Rouillon, M Parodi, A De Lamaze, I Prang, V Couloigner, F Denoyelle, N Loundon
Eur Ann Otorhinolaryngol Head Neck Dis, 2021 Oct, PMID: 33495071 DOI: 10.1016/j.anorl.2021.01.002
– The role of computed tomography and magnetic resonance imaging for preoperative pediatric cochlear implantation work-up in academic institutions.
Art A Ambrosio, Natalie Loundon, Daniel Vinocur, Peter Kruk, Hubert Ducou Le Pointe, Francois Chalard, Matthew Zapala, Daniela Carvalho
Cochlear Implants Int, 2021 Mar, PMID: 33043845 DOI: 10.1080/14670100.2020.1830239
– Telemedicine in Audiology. Best practice recommendations from the French Society of Audiology (SFA) and the French Society of Otorhinolaryngology-Head and Neck Surgery (SFORL).
H Thai-Van, D Bakhos, D Bouccara, N Loundon, M Marx, T Mom, I Mosnier, S Roman, C Villerabel, C Vincent, F Venail
Eur Ann Otorhinolaryngol Head Neck Dis, 2021 Oct, PMID: 33097467 PMCID: PMC7575454 DOI: 10.1016/j.anorl.2020.10.007
– Dopachrome tautomerase variants in patients with oculocutaneous albinism.
Perrine Pennamen, Angèle Tingaud-Sequeira, Iveta Gazova, Margaret Keighren, Lisa McKie, Sandrine Marlin, Souad Gherbi Halem, Josseline Kaplan, Cédric Delevoye, Didier Lacombe, Claudio Plaisant, Vincent Michaud, Eulalie Lasseaux, Sophie Javerzat, Ian Jackson, Benoit Arveiler
Genet Med, 2021 Mar, PMID: 33100333 DOI: 10.1038/s41436-020-00997-8
– Arterial spin labeling brain MRI study to evaluate the impact of deafness on cerebral perfusion in 79 children before cochlear implantation.
Arnaud Coez, Ludovic Fillon, Ana Saitovitch, Caroline Rutten, Sandrine Marlin, Jennifer Boisgontier, Alice Vinçon-Leite, Hervé Lemaitre, David Grévent, Charles-Joris Roux, Volodia Dangouloff-Ros, Raphaël Levy, Eric Bizaguet, Isabelle Rouillon, Eréa Noël Garabédian, Françoise Denoyelle, Monica Zilbovicius, Natalie Loundon, Nathalie Boddaert
Neuroimage Clin, 2021, PMID: 33369563 PMCID: PMC7777537 DOI: 10.1016/j.nicl.2020.102510
– Long-term outcomes of cartilage tympanoplasty in 139 ears in children.
François Simon, Briac Thierry, Tioka Rabeony, Florian Verrier, Caroline Elie, Natalie Loundon, Nicolas Leboulanger, Vincent Couloigner, Erea-Noël Garabedian, Françoise Denoyelle
Clin Otolaryngol, 2021 Nov, PMID: 33993647 DOI: 10.1111/coa.13801
– [Neonatal hearing screening].
Françoise Denoyelle, Isabelle Rouillon, Fiona Alvin, Marine Parodi, Vincent Couloigner, Natalie Loundon, Noël Garabédian
Med Sci (Paris), 2021 May, PMID: 34003098 DOI: 10.1051/medsci/2021064
– Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss.
Sissy Bassani, Edward van Beelen, Mireille Rossel, Norine Voisin, Anna Morgan, Yoan Arribat, Nicolas Chatron, Jacqueline Chrast, Massimiliano Cocca, Benjamin Delprat, Flavio Faletra
Hum Mol Genet, 2021 Sep 15, PMID: 34059922 DOI: 10.1093/hmg/ddab145
2020
– The French Cochlear Implant Registry (EPIIC): Perception and language results in infants with cochlear implantation under the age of 24 months.
N Loundon, F Simon, K Aubry, P Bordure, A Bozorg-Grayeli, O Deguine, C Eyermann, V Franco-Vidal 8, B Godey, N Guevara, A Karkas, N Klopp, M Labrousse, J-P Lebreton, Y Lerosey, E Lescanne, R Marianowski, F Merklen, K Mezouaghi, T Mom, S Moreau, I Mosnier, N Noël-Petroff, C Parietti-Winkler, P Piller, C Poncet, E Radafy, S Roman, S Roux-Vaillard, S Schmerber, L Tavernier, E Truy, C Vincent, A De Lamaze
Eur Ann Otorhinolaryngol Head Neck Dis, 2020 Sep, PMID: 32863156 DOI: 10.1016/j.anorl.2020.07.010
– MED12 missense mutation in a three-generation family. Clinical characterization of MED12-related disorders and literature review.
Elisa Rubinato, Sophie Rondeau, Fabienne Giuliano, Manoelle Kossorotoff, Marine Parodi, Souad Gherbi, Julie Steffan, Laurence Jonard, Sandrine Marlin
Eur J Med Genet, 2020 Mar, PMID: 31536828 DOI: 10.1016/j.ejmg.2019.103768
– Heimler Syndrome.
S Mechaussier, I Perrault, H Dollfus, A Bloch-Zupan, N Loundon, L Jonard, S Marlin
Adv Exp Med Biol, 2020, PMID: 33417209 DOI: 10.1007/978-3-030-60204-8_7
– PRPS1 loss-of-function variants, from isolated hearing loss to severe congenital encephalopathy: New cases and literature review.
Oriane Mercati, Marie-Thérèse Abi Warde, Geneviève Lina-Granade, Marlène Rio, Solveig Heide, Pascale de Lonlay, Irène Ceballos-Picot, Matthieu P Robert, Vincent Couloigner, Jacques Beltrand, Nathalie Boddaert, Diana Rodriguez, Elisa Rubinato, Jean-Michel Lapierre, Christophe Merlette, Sylvia Sanquer, Agnès Rötig, Holger Prokisch, Stanislas Lyonnet, Natalie Loundon, Josseline Kaplan, Jean-Paul Bonnefont, Arnold Munnich, Claude Besmond, Laurence Jonard, Sandrine Marlin
Eur J Med Genet, 2020 Nov, PMID: 32781272 DOI: 10.1016/j.ejmg.2020.104033
– Mutation m.3395A > G in MT-ND1 leads to variable pathologic manifestations.
Nicolás Gutiérrez Cortés, Claire Pertuiset, Elodie Dumon, Marine Börlin, Barbara Da Costa, Marina Le Guédard, Tanya Stojkovic, Natalie Loundon, Isabelle Rouillon, Yann Nadjar, Thierry Letellier, Laurence Jonard, Sandrine Marlin, Christophe Rocher
Hum Mol Genet, 2020 Apr 15, PMID: 32011699 DOI: 10.1093/hmg/ddaa020
– Psychosocial determinants associated with quality of life in people with usher syndrome. A scoping review.
Marine Arcous, Olivier Putois, Sophie Dalle-Nazébi, Sylvain Kerbourch, Anaelle Cariou, Ines Ben Aissa, Sandrine Marlin, Rémy Potier
Disabil Rehabil, 2020 Sep, PMID: 30974979 DOI: 10.1080/09638288.2019.1571637
2017
– EDNRB mutations cause Waardenburg syndrome type II in the heterozygous state.
Issa, N. Bondurand, E. Faubert, S. Poisson, L. Lecerf, P. Nitschke, N. Deggouj, N. Loundon, L. Jonard, A. David, Y Sznajer, P. Blanchet , S. Marlin, V. Pingault.
Hum Mutat. 2017 May, PMID: 28236341 DOI: 10.1002/humu.23206
– FDXR Mutations cause sensorial neuropathies and expand the spectrum of mitochondrial Fe-S-Synthesis diseases
Paul, A. Drecourt, F. Petit, D.D. Deguine, C. Vasnier, M. Oufadem, C. Masson, C. Bonnet, S. Mahmoudi, I. Mosnier, L. Mahieu, D. Bouccara, J. Kaplan, G. Challe, C. Domange, F. Mochel, O. Sterkers, S. Gerber, P. Nitschke, C. Bole-Feysot, L. Jonard, S. Gherbi, O. Mercati, I. Ben Aissa, S. Lyonnet, A. Rötig, A. Delahodde, S. Marlin.
Am J Hum Genet. 2017 Oct 5, PMID: 28965846 PMCID: PMC5630197 DOI: 10.1016/j.ajhg.2017.09.007
– Mutations in TUBB4B cause a distinctive sensorineural disease.
R. Luscan, S. Mechaussier, A. Paul, G. Tian, X. Gerard, S. Defoort-Dellhemmes, N. Loundon, I. Audo, S. Bonnin, J.-F. Le Gargasson, J. Dumont, N. Goudin, M. Garfa-Traoré, M. Bras, A. Pouliet, B. Bessieres, N. Boddaert, J. -A. Sahel, S. Lyonnet, J. Kaplan, N.-J. Cowan, J.-M. Rozet, S. Marlin, I. Perrault.
Am J Hum Genet. 2017 Dec, PMID: 29198720 PMCID: PMC5812887 DOI: 10.1016/j.ajhg.2017.10.010
2020
– Surdités génétiques
S. Marlin, , F. Denoyelle
Elsevier Masson Consulte, 2016, Doi : 10.1016/S0246-0351(16)58505-5
– An Application of NGS for Molecular Investigations in Perrault Syndrome: Study of 14 Families and Review of the Literature
Lerat, L. Jonard, N. Loundon, S. Christin-Maitre, D. Lacombe, C. Goizet, C. Rouzier, L. Van Maldergem, S. Gherbi, E.N. Garabedian, J.-P. Bonnefont, P. Touraine, I. Mosnier, A. Munnich, F. Denoyelle, S. Marlin.
Hum Mutat. 2016 Dec, PMID: 27650058 DOI: 10.1002/humu.23120
2023
Mᵉ Duchemin: a lawyer who is deaf but not speechless, thanks to artificial intelligence
L’Obs | 03.07.2024
Pauline Duchemin is deaf. But with his Californian start-up, her brother, Thibault, has given her precious autonomy to complete her law studies. And even litigate. Read more >
2021
Early hearing loss: at least 500 forms of genetic deafness
Le Dauphiné libéré | 03.17.2021
There are hundreds of them, and sometimes affect from birth: early forms of deafness are the subject of research that is akin to painstaking work. > Read more
Deafness in children: 80% of early forms of genetic origin
Le Progrès | 03.17.2021
The majority of hearing loss diagnosed in newborns and children is genetic. 200 genes are indeed identified in the occurrence of this handicap. > Read more
Deafness: early forms often genetic
Sud Ouest | 03.11.2021
In France, deafness affects 1 in 1,000 children at birth and 1 in 700 before adulthood. A point raised by Imagine, the Institute of Genetic Diseases, on the occasion of the National Hearing Day organized this Thursday, March 11. > Read more
Deafness: early forms, often genetic
La Dépêche |03.11.2021
The majority of deafness diagnosed in newborns and children is genetic in origin. A total of 200 genes have been identified in the development of this disorder. Let’s take stock of the situation on the occasion of the National Hearing Day organized on March 11. > Read more
2017
What do we pass on genetically to our children?
Le Figaro madame | 07.07.2017
Physical appearance and intelligence are transmitted through genes. But still ? Responses from Sandrine Marlin, geneticist. > Read more
2016
Sandrine Marlin dialogue avec les sourds
Le Monde Science et Techno | This specialist in genetic forms of deafness wants to stay in contact with patients to feed her research on hearing disorders. > Read more
Coordinating center
AP-HP Necker – Enfants malades hospital
Genetics department – Dr Sandrine Marlin
149, rue de Sèvres – 75743 Paris cedex 15
Phone. +33 (0)1 71 39 69 04
Email : genetique.surdite.nck@aphp.fr
Constituent centers
AP-HP Pitié-Salpêtrière university hospital
Dr Isabelle Mosnier
47-83 boulevard de l’Hôpital, 75651 Paris
Phone. +33 (0)1 84 82 78 47
Email : secretariat-orl.maladies-rares-psl@aphp.fr
AP-HP Lariboisière hospital
Dr Charlotte Hautefort
2 rue Ambroise-Paré, 75010 Paris
Phone. +33 (0)1 49 95 80 64
Email : charlotte.hautefort@aphp.fr
Lille CHRU
Dr Catherine Vincent-Delorme
2 avenue Oscar Lambret, 59037 Lille Cedex
Phone. +33 (0)3 20 44 49 11
Email : surditegenetique@chu-lille.fr
Toulouse university hospital, Purpan
Dr Delphine Dupin-Deguine
2 rue Viguerie, 31059 Toulouse Cedex 09
Phone. +33 (0)5 61 77 71 94
Email : crcm.surdite@chu-toulouse.fr
Montpellier university hospital, Gui de Chauliac hospital
Pr Michel Mondain
80 avenue Augustin Fliche, 34295 Montpellier cedex 5
Phone. +33 (0)4 67 33 68 04
Email : orlb@chu-montpellier.fr
Competence centers
AP-HM, Timone Child CHU
Dr Sabine Sigaudy
264 rue Saint-Pierre, 13005 Marseille
Phone. +33 (0)4 91 38 67 49
Email : rdv.genetiquemedicale@ap-hm.fr
AP-HP, Robert-Debré university hospital
Dr Laurence Perrin
48 boulevard Sérurier, 75019 Paris
Phone. +33 (0)1 40 03 36 18
Email : laurence.perrin2@aphp.fr
Grenoble Alpes CHU
Dr Klauss Dietrich
Avenue des maquis du Grésivaudan, 38700 La Tronche
Phone. +33 (0)4 76 76 72 85
Email : secretariatgenetiqueclinique@chu-grenoble.fr
Nantes CHU , Hotel Dieu
Dr Marie Vincent
1 place Alexis Ricordeau, 44093 Nantes Cedex
Phone. +33 (0)2 40 08 32 45
Email : bp-secretairat-genetique-clinique@chu-nantes.fr
Angers CHU
Dr Estelle Colin
4 rue Larrey, 49100 Angers
Phone. +33 (0)2 41 35 38 83
Email : consultationgenetique@chu-angers.fr
Rouen university hospital
Dr Anne-Marie Gerrault
37 boulevard Gambetta, 76031 Rouen Cedex
Phone. +33(0)2 32 88 87 47
Email : anne-marie.guerrot@chu-rouen.fr
St Etienne CHU, North Hospital
Dr Renaud Touraine
Avenue Albert Raimond, 42055 Saint Etienne
Phone. +33(0)4 77 82 81 16
Email : genetique.hn@chu-st-etienne.fr
Dijon CHU, Children’s Hospital
Dr Sophie Nambot
14 rue Gaffarel, 21079 Dijon Cedex
Phone. +33 (0)3 80 29 53 13
Email : sophie.nambot@chu-dijon.fr
Tours CHRU, Bretonneau Hospital
Pr Annick Toutain
2 boulevard Tonnelé, 37044 Tours Cedex 9
Phone. +33 (0)2 47 47 88 50
Email : genetique.clinique@chu-tours.fr
Reunion CH, South site
Dr Marta Spodenkiewicz
97 avenue du président Mitterand, 97448 Saint-Pierre Cedex
Phone. +33 (0)2 62 71 78 70
Email : sec.genetique.sud@chu-reunion.fr
Clermont-Ferrand CHU, Estaing
Dr Fanny Laffargue
1 place Lucie et Raymond Aubrac, 63003 Clermont-Ferrand
Phone. +33 (0)4 73 75 06 53
Email : crmrsurditegenetique@chu-clermontferrand.fr
Le Mans CH
Dr Radka Stoeva
194 avenue Rubillard, 72037 Le Mans Cedex
Phone. +33 (0)2 44 71 01 84
Email : glabo@ch-lemans.fr
Nancy CHRU, Children’s hospital
Dr Laetitia Lambert
29 avenue du Maréchal de Lattre de Tassigny, 54035 Nancy Cedex
Phone. +33 (0)3 83 15 36 22
Email : sec-gen-clinique@chru-nancy.fr
Lyon Civil Hospices
Dr Charles-Patrick Edery
3 quai des Célestins, 69002 Lyon
Phone. +33 (0)4 72 12 96 98
Email : Charles-patrick.edery@chu-lyon.fr
Reims university hospital, white house hospital
Dr Céline Poirsier
47 rue Cognacq Jay, 51092 Reims Cedex
Phone. +33 (0)3 26 78 78 50
Email : vmeyer@chu-reims.fr
Rennes university hospital, Pontchaillou hospital
Dr Marion Blanchard
2 rue Henri Le Guilloux, 35000 Rennes
Phone. +33 (0)2 99 28 42 85
Email : marion.blanchard@chu-rennes.fr
Besançon CHU, Jean Minjoz
Dr Juliette Piard
3 boulevard Fleming, 25000 Besançon
Phone. +33 (0)3 81 21 81 87
Email : cgh@chu-besancon.fr
Strasbourg HUS, Hautepierre hospital
Pr Hélène Dollfus
1 place de l’Hôpital, BP 426, 67091 Strasbourg
Phone. +33 (0)3 69 55 19 55
Email : igma@chru-strasbourg.fr
Bordeaux university hospital, Pellegrin hospital
Dr Marine Legendre
Place Amélie Raba Léon, 33076 Bordeaux Cedex
Phone. +33 (0)5 57 82 03 45
Email : marine.legendre@chu-bordeaux.fr
- Génération cochlée
- Union Nationale des Associations de Parents d’Enfants Déficients Auditifs (UNAPEDA)
- Association nationale pour la Langue française Parlée Complétée (ALPC)
- Association contre les Maladies Mitochondriales (AMMI)
- Génération 22
- S’entendre
- Centre d’Information Sur l’Implant Cochléaire (CISIC)
- Retina France
- Bucodes SurdiFrance
- Fédération nationale pour l’Inclusion des personnes en situation de Handicap Sensoriel et DYS en France (FISAF)
- Action Connaissance Formation pour la Surdité (ACFOS)
CRESAM is a structure that pursues an original project at the service of children and adults suffering from double sensory deficiency.
The CNRHR Robert Laplane has a role of specific clinical expertise, transfer and development of competences, animation of specialized networks as well as formalization and diffusion of knowledge concerning the situations of rare handicap concerning deaf children.
For information on deafness, parents of deaf children and people with hearing loss have a national system consisting of a telephone platform (0812 040 040) and a website.
All about Usher syndrome
Acfos dedicates its action to knowledge and training about deafness, mainly congenital or acquired during childhood.
FISAF, the national federation for the inclusion of people with sensory disabilities and DYS disorders in France, created in 1925, recognized as being of public utility, federates 180 associations, establishments and services that welcome, train and accompany more than 16,000 people with sensory disabilities and DYS disorders with or without associated handicaps thanks to a network of 6,000 professionals representing more than 50 professions.
Screening and prevention of hearing impairment in adults
Screening and prevention of hearing impairment in children
Definition, prevalence and semantics of hearing disorders
Etiologies, differential diagnostics of deafness – Watch points
How do I communicate with a deaf/hard of hearing person? Hearing rehabilitation
How do I communicate with a deaf/hard of hearing person?
Reception of a deaf patient with suspicion of COVID-19
Genetic deafness explained to children
Contact information
Necker-Enfants malades university hospital
> Clinical genetics department
149 rue de Sèvres
75743 PARIS Cedex 15
In Necker, the reference center for genetic deafness in brief …
* data valid for 2022
